Protein Family Models

This domain, formerly known as DUF2337, is found at the C-terminal end of the anti-sigma-K factor from Mycobacterium tuberculosis (RskA), which positively regulates expression of the antigenic proteins MPB70 and MPB83 [1,2]. [1]. 17064366. Mutations in Mycobacterium tuberculosis Rv0444c, the gene encoding anti-SigK, explain high level expression of MPB70 and MPB83 in Mycobacterium bovis. Said-Salim B, Mostowy S, Kristof AS, Behr MA;. Mol Microbiol. 2006;62:1251-1263. [2]. 24699647. Structural basis for the redox sensitivity of the Mycobacterium tuberculosis SigK-RskA sigma-anti-sigma complex. Shukla J, Gupta R, Thakur KG, Gokhale R, Gopal B;. Acta Crystallogr D Biol Crystallogr. 2014;70:1026-1036. (from Pfam)

Date:

2024-10-16

anti-sigma factor similar to mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor similar to mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor similar to mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor such as mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor such as mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor similar to mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor such as mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor such as mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor similar to mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor similar to mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor similar to mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor such as mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor such as mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor similar to mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor such as mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor which has a putative zinc finger domain and may bind zinc; its anti-sigma factor domain is similar to mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; zf-HC2 domain-containing anti-sigma factor; anti-sigma factor similar to mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor similar to mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor such as mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor such as mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor similar to mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor such as mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor similar to mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor similar to mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor such as mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor such as mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor which has a putative zinc finger domain and may bind zinc; its anti-sigma factor domain is similar to mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor similar to mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis; anti-sigma factor such as mycobacterial anti-sigma-K factor RskA, an anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK; ECF sigma factors are held in an inactive form by an anti-sigma factor until r

Date:

2017-03-02