Protein Family Models for Protein (Select 654546230) - Protein Family Models

Select item 4374461.

SLC13 (solute carrier 13) family permease is a sodium-coupled symporter that facilitates the transport across biological membranes of various ions including sulfate or Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate; may function as a regulator

Date:: 2024-07-23

Family Accession:: 18423072
Method:: Sparcle

Select item 4188242.

TRAP transporter large permease subunit

This family contains a diverse range of predicted transporter proteins. Including the DctM subunit of the bacterial and archaeal TRAP C4-dicarboxylate transport (Dct) system permease. In general, C4-dicarboxylate transport systems allow C4-dicarboxylates like succinate, fumarate, and malate to be taken up. TRAP C4-dicarboxylate carriers are secondary carriers that use an electrochemical H+ gradient as the driving force for transport. DctM is an integral membrane protein that is one of the constituents of TRAP carriers [1]. Note that many family members are hypothetical proteins. [1]. 11803016. C4-dicarboxylate carriers and sensors in bacteria. Janausch IG, Zientz E, Tran QH, Kroger A, Unden G;. Biochim Biophys Acta 2002;1553:39-56. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF018513.5
Method:: HMM

Select item 4134203.

TrkA C-terminal domain-containing protein

This domain is often found next to the Pfam:PF02254 domain. The exact function of this domain is unknown. It has been suggested that it may bind an unidentified ligand [1]. The domain is predicted to adopt an all beta structure [1]. [1]. 11292341. Regulatory potential, phyletic distribution and evolution of ancient, intracellular small-molecule-binding domains. Anantharaman V, Koonin EV, Aravind L;. J Mol Biol 2001;307:1271-1292. (from Pfam)

GO Terms:

Biological Process:: potassium ion transport (GO:0006813)

Molecular Function:: monoatomic cation transmembrane transporter activity (GO:0008324)

Date:: 2024-10-16

Family Accession:: NF014171.5
Method:: HMM

Select item 4131154.

SLC13 family permease

The SLC13 family permease is also known as DASS (Divalent Anion:Na+ Symporter). Characterized members are symporters of a substrate anion with sodium cations.

GO Terms:

Cellular Component:: membrane (GO:0016020)

Biological Process:: transmembrane transport (GO:0055085)

Date:: 2024-08-14

Family Accession:: NF015557.5
Method:: HMM

Select item 4118615.

anion permease

There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1. (from Pfam)

GO Terms:

Cellular Component:: membrane (GO:0016020)

Molecular Function:: transmembrane transporter activity (GO:0022857)

Biological Process:: transmembrane transport (GO:0055085)

Date:: 2024-08-14

Family Accession:: NF013132.5
Method:: HMM

Select item 3979676.