Protein Family Models

This domain is found at the C-terminal end of Sucrose hydrolase from Xanthomonas campestris (SupH, Swiss:Q6UVM5) and similar bacterial sequences. SupH shows a central domain that consists of an eight-stranded alpha/beta barrel (Pfam:PF00128). This beta-stranded domain is located on a side of the barrel fold [1]. Paper describing PDB structure 2wpg. [1]. 19966417. The apo structure of sucrose hydrolase from Xanthomonas campestris pv. campestris shows an open active-site groove. Champion E, Remaud-Simeon M, Skov LK, Kastrup JS, Gajhede M, Mirza O;. Acta Crystallogr D Biol Crystallogr. 2009;65:1309-1314. (from Pfam)

Date:

2024-10-16

Alpha amylase is classified as family 13 of the glycosyl hydrolases. The structure is an 8 stranded alpha/beta barrel containing the active site, interrupted by a ~70 a.a. calcium-binding domain protruding between beta strand 3 and alpha helix 3, and a carboxyl-terminal Greek key beta-barrel domain. [1]. 8107092. Refined molecular structure of pig pancreatic alpha-amylase at 2.1 A resolution. Larson SB, Greenwood A, Cascio D, Day J, McPherson A;. J Mol Biol 1994;235:1560-1584. [2]. 9600843. Crystal structure of yellow meal worm alpha-amylase at 1.64 A resolution. Strobl S, Maskos K, Betz M, Wiegand G, Huber R, Gomis-Ruth FX, Glockshuber R;. J Mol Biol 1998;278:617-628. (from Pfam)

Date:

2024-10-16

alpha-amylase family protein similar to trehalose synthase that catalyzes the reversible interconversion of trehalose and maltose; belongs to the glycoside hydrolase 13 family

Date:

2021-03-25