Protein Family Models for Protein (Select 654931924) - Protein Family Models

Select item 4236271.

Date:: 2024-08-14

Family Accession:: NF024635.5
Method:: HMM

Select item 4221952.

This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF025052.5
Method:: HMM

Select item 4172293.

Chloramphenicol phosphotransferase-like protein

The members of this family are all similar to chloramphenicol 3-O phosphotransferase (CPT, Swiss:Q56148) expressed by Streptomyces venezuelae. Chloramphenicol (Cm) is a metabolite produced by this bacterium that can inhibit ribosomal peptidyl transferase activity and therefore protein production. By transferring a phosphate group to the C-3 hydroxyl group of Cm, CPT inactivates this potentially lethal metabolite [1]. [1]. 11468347. Structural basis for chloramphenicol tolerance in Streptomyces. venezuelae by chloramphenicol phosphotransferase activity.. Izard T;. Protein Sci 2001;10:1508-1513. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF019544.5
Method:: HMM

Select item 4164594.

zeta toxin family protein

This family consists of several bacterial zeta toxin proteins. Zeta toxin is thought to be part of a postregulational killing system in bacteria. It relies on antitoxin/toxin systems that secure stable inheritance of low and medium copy number plasmids during cell division and kill cells that have lost the plasmid [1]. [1]. 12571357. Crystal structure of the plasmid maintenance system. epsilon/zeta: functional mechanism of toxin zeta and. inactivation by epsilon 2 zeta 2 complex formation.. Meinhart A, Alonso JC, Strater N, Saenger W;. Proc Natl Acad Sci U S A 2003;100:1661-1666. (from Pfam)

GO Terms:

Molecular Function:: ATP binding (GO:0005524)

Molecular Function:: kinase activity (GO:0016301)

Date:: 2024-08-14

Family Accession:: NF018154.5
Method:: HMM

Select item 4004735.