Protein Family Models for Protein (Select 655375459) - Protein Family Models

Select item 4243481.

glutathione S-transferase family protein

This domain is closely related to Pfam:PF00043. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF025850.5
Method:: HMM

Select item 4226772.

Glutathione S-transferase, N-terminal domain

This family is closely related to Pfam:PF02798. (from Pfam)

GO Terms:

Molecular Function:: protein binding (GO:0005515)

Biological Process:: glutathione metabolic process (GO:0006749)

Date:: 2024-08-14

Family Accession:: NF024801.5
Method:: HMM

Select item 4220673.

glutathione S-transferase C-terminal domain-containing protein

This domain is closely related to Pfam:PF00043. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF024802.5
Method:: HMM

Select item 4217824.

glutathione S-transferase N-terminal domain-containing protein

GO Terms:

Molecular Function:: protein binding (GO:0005515)

Biological Process:: glutathione metabolic process (GO:0006749)

Date:: 2024-08-14

Family Accession:: NF024809.5
Method:: HMM

Select item 4129915.

Glutathione S-transferase, N-terminal domain

Function: conjugation of reduced glutathione to a variety of targets. Also included in the alignment, but not GSTs: S-crystallins from squid (similarity to GST previously noted); eukaryotic elongation factors 1-gamma (not known to have GST activity and similarity not previously recognised); HSP26 family of stress-related proteins including auxin-regulated proteins in plants and stringent starvation proteins in E. coli (not known to have GST activity and similarity not previously recognised). The glutathione molecule binds in a cleft between the N- and C-terminal domains - the catalytically important residues are proposed to reside in the N-terminal domain [1]. [1]. 9680481. Three-dimensional structure of Escherichia coli glutathione S-transferase complexed with glutathione sulfonate: catalytic roles of Cys10 and His106. Nishida M, Harada S, Noguchi S, Satow Y, Inoue H, Takahashi K;. J Mol Biol 1998;281:135-147. (from Pfam)

GO Terms:

Molecular Function:: protein binding (GO:0005515)

Biological Process:: glutathione metabolic process (GO:0006749)

Date:: 2024-10-16

Family Accession:: NF014816.5
Method:: HMM

Select item 4109156.

glutathione binding-like protein

Members of this family include glutathione S-transferases, glutathione-dependent disulfide bond oxidoreductases, and some proteins not known to interact with glutathione, although most of the latter set score only a little above cutoffs for the model.

Date:: 2024-10-16

Family Accession:: NF012273.5
Method:: HMM

Select item 4029947.