Protein Family Models for Protein (Select 664526975) - Protein Family Models

Select item 4275561.

Yop-YscD-cpl is the cytoplasmic domain of Yop proteins like YscD from Proteobacteria. YscD forms part of the inner membrane component of the bacterial type III secretion injectosome apparatus [1,2]. [1]. 1860816. Analysis of virC, an operon involved in the secretion of Yop proteins by Yersinia enterocolitica. Michiels T, Vanooteghem JC, Lambert de Rouvroit C, China B, Gustin A, Boudry P, Cornelis GR;. J Bacteriol 1991;173:4994-5009. [2]. 22349221. Structure of the cytoplasmic domain of Yersinia pestis YscD, an essential component of the type III secretion system. Lountos GT, Tropea JE, Waugh DS;. Acta Crystallogr D Biol Crystallogr. 2012;68:201-209. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF028007.5
Method:: HMM

Select item 4117022.

FtsK/SpoIIIE domain-containing protein

FtsK has extensive sequence similarity to wide variety of proteins from prokaryotes and plasmids [1], termed the FtsK/SpoIIIE family. This domain contains a putative ATP binding P-loop motif. It is found in the FtsK cell division protein from E. coli Swiss:P46889 and the stage III sporulation protein E SpoIIIE Swiss:P21458 which has roles in regulation of prespore specific gene expression in B. subtilis. A mutation in FtsK causes a temperature sensitive block in cell division and it is involved in peptidoglycan synthesis or modification [1]. The SpoIIIE protein is implicated in intercellular chromosomal DNA transfer [1]. [1]. 7592387. A new Escherichia coli cell division gene, ftsK. Begg KJ, Dewar SJ, Donachie WD;. J Bacteriol 1995;177:6211-6222. [2]. 8160014. Bacillus subtilis spoIIIE protein required for DNA segregation during asymmetric cell division. Wu LJ ,Errington J;. Science 1994;264:572-575. (from Pfam)

GO Terms:

Molecular Function:: nucleotide binding (GO:0000166)

Molecular Function:: DNA binding (GO:0003677)

Molecular Function:: ATP binding (GO:0005524)

Date:: 2024-10-16

Family Accession:: NF013727.5
Method:: HMM

Select item 4110053.

FHA domain-containing protein

The FHA (Forkhead-associated) domain is a phosphopeptide binding motif [2]. [1]. 7482699. The FHA domain: a putative nuclear signalling domain found in protein kinases and transcription factors. Hofmann K, Bucher, P;. Trends Biochem Sci 1995;20:347-349. [2]. 10518219. The FHA domain is a modular phosphopeptide recognition motif. Durocher D, Henckel J, Fersht AR, Jackson SP;. Mol Cell. 1999;4:387-394. [3]. 12564991. Bacterial FHA domains: neglected players in the phospho-threonine signalling game?. Pallen M, Chaudhuri R, Khan A;. Trends Microbiol 2002;10:556-563. (from Pfam)

GO Terms:

Molecular Function:: protein binding (GO:0005515)

Date:: 2024-10-16

Family Accession:: NF012708.5
Method:: HMM

Select item 4040054.