Protein Family Models for Protein (Select 694110668) - Protein Family Models

Select item 4236591.

This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins. [1]. 9175471. GCN5-related histone N-acetyltransferases belong to a diverse superfamily that includes the yeast SPT10 protein. Neuwald AF, Landsman D;. Trends Biochem Sci 1997;22:154-155. [2]. 11893502. A second catalytic domain in the Elp3 histone acetyltransferases: a candidate for histone demethylase activity?. Chinenov Y;. Trends Biochem Sci 2002;27:115-117. (from Pfam)

GO Terms:

Molecular Function:: acyltransferase activity, transferring groups other than amino-acyl groups (GO:0016747)

Date:: 2024-10-16

Family Accession:: NF025054.5
Method:: HMM

Select item 4226852.

GNAT family N-acetyltransferase

This domain catalyses N-acetyltransferase reactions. (from Pfam)

GO Terms:

Molecular Function:: acyltransferase activity, transferring groups other than amino-acyl groups (GO:0016747)

Date:: 2024-08-14

Family Accession:: NF024898.5
Method:: HMM

Select item 4216993.

MarR family transcriptional regulator

The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds [1]. The structure of MarR is known [2] and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif. [1]. 9068629. The Salmonella typhimurium mar locus: molecular and genetic analyses and assessment of its role in virulence. Sulavik MC, Dazer M, Miller PF;. J Bacteriol 1997;179:1857-1866. [2]. 11473263. The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 A resolution. Alekshun MN, Levy SB, Mealy TR, Seaton BA, Head JF;. Nat Struct Biol 2001;8:710-714. (from Pfam)

GO Terms:

Molecular Function:: DNA-binding transcription factor activity (GO:0003700)

Biological Process:: regulation of DNA-templated transcription (GO:0006355)

Date:: 2024-10-16

Family Accession:: NF024212.5
Method:: HMM

Select item 4118704.

MarR family transcriptional regulator

The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds [1]. The structure of MarR is known [2] and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif. [1]. 9068629. The Salmonella typhimurium mar locus: molecular and genetic analyses and assessment of its role in virulence. Sulavik MC, Dazer M, Miller PF;. J Bacteriol 1997;179:1857-1866. [2]. 11473263. The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 A resolution. Alekshun MN, Levy SB, Mealy TR, Seaton BA, Head JF;. Nat Struct Biol 2001;8:710-714. (from Pfam)

GO Terms:

Molecular Function:: DNA-binding transcription factor activity (GO:0003700)

Biological Process:: regulation of DNA-templated transcription (GO:0006355)

Date:: 2024-10-16

Family Accession:: NF013231.5
Method:: HMM

Select item 4114485.

GNAT family N-acetyltransferase

This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins. [1]. 9175471. GCN5-related histone N-acetyltransferases belong to a diverse superfamily that includes the yeast SPT10 protein. Neuwald AF, Landsman D;. Trends Biochem Sci 1997;22:154-155. [2]. 11893502. A second catalytic domain in the Elp3 histone acetyltransferases: a candidate for histone demethylase activity?. Chinenov Y;. Trends Biochem Sci 2002;27:115-117. (from Pfam)

GO Terms:

Molecular Function:: acyltransferase activity, transferring groups other than amino-acyl groups (GO:0016747)

Date:: 2024-10-16

Family Accession:: NF012792.5
Method:: HMM

Select item 4029596.