Protein Family Models

TraN is a large cysteine-rich outer membrane protein involved in the mating-pair stabilisation (adhesin) component of the F-type conjugative plasmid transfer system. TraN is believed to interact with the core type IV secretion system apparatus through the TraV protein [1][2][3]. [1]. 1593622. Characterization of the F plasmid mating aggregation gene traN and of a new F transfer region locus trbE. Maneewannakul S, Kathir P, Ippen-Ihler K;. J Mol Biol 1992;225:299-311. [2]. 12855161. F factor conjugation is a true type IV secretion system. Lawley TD, Klimke WA, Gubbins MJ, Frost LS;. FEMS Microbiol Lett. 2003;224:1-15. [3]. 16138100. Mobile genetic elements: the agents of open source evolution. Frost LS, Leplae R, Summers AO, Toussaint A;. Nat Rev Microbiol. 2005;3:722-732. (from Pfam)

Gene:

traN

Date:

2024-10-16

conjugal transfer protein TraN is involved in stabilizing mating pairs during plasmid conjugation; F plasmid TraN appears to recognize OmpA in the recipient cell

Date:

2017-12-06

Gene:

traN

Date:

2020-10-26