Protein Family Models

Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with Pfam:PF01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function. (from Pfam)

Date:

2024-08-14

Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family Pfam:PF02371. [1]. 1324903. A Coxiella burnetti repeated DNA element resembling a bacterial insertion sequence. Hoover TA, Vodkin MH, Williams JC;. J Bacteriol 1992;174:5540-5548. [2]. 2403542. Sequence analysis of the inversion region containing the pilin genes of Moraxella bovis. Fulks KA, Marrs CF, Stevens SP, Green MR;. J Bacteriol 1990;172:310-316. (from Pfam)

Date:

2024-10-16

IS110 family transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Date:

2024-07-02

Proteins of this family are DEDD (Asp, Glu, Asp, Asp) type transposases, which are encoded by the IS110 family elements.

Date:

2022-03-28

Date:

2019-09-10