Protein Family Models

This family consists of Carbon starvation protein CstA a predicted membrane protein. It has been suggested that CstA is involved in peptide utilisation [1]. [1]. 1848300. Molecular and functional characterization of a carbon starvation gene of Escherichia coli. Schultz JE, Matin A;. J Mol Biol 1991;218:129-140. [2]. 12867454. CsrA regulates translation of the Escherichia coli carbon starvation gene, cstA, by blocking ribosome access to the cstA transcript. Dubey AK, Baker CS, Suzuki K, Jones AD, Pandit P, Romeo T, Babitzke P;. J Bacteriol. 2003;185:4450-4460. [3]. 29358499. Peptide Transporter CstA Imports Pyruvate in Escherichia coli K-12. Hwang S, Choe D, Yoo M, Cho S, Kim SC, Cho S, Cho BK;. J Bacteriol. 2018;200:e00771-e00717. (from Pfam)

Date:

2024-10-16

carbon starvation protein A may be involved in peptide utilization

Date:

2017-02-03

CstA (carbon starvation protein A), like its paralog BtsT (YjiY) that is also found in E. coli, is a pyruvate/proton symporter. It is regularly found encoded next to a small protein, YbdD, which appears to be another component of the transporter. Both YbdD and its paralog YjiX are notable for terminating with a Cys-Cys dipeptide, replaced by Cys-Sec in Epsilonproteobacteria such as Campylobacter and Helicobacter, where YbdD homologs are selenoproteins.

Gene:

cstA

Date:

2022-03-23