Protein Family Models

FetB (Fe Transport B) is one subunit of the iron efflux ABC transporter FetAB. FetA is the ATP-binding subunit and FetB is the permease subunit. Note that model originally was defined more broadly, with membership including a number of proteins distinct in function from FetB, but has now been narrowed. All members of the seed alignment occur in the Enterobacterales and are encoded next to FetA.

Gene:

fetB

Date:

2024-09-15

Characterised proteins in this family include probable iron export permease protein FetB, which is part of the ABC transporter complex FetAB, probably involved in iron export [1], and aluminium sensitive 3 protein, also part of an ABC transporter required for aluminum (Al) resistance [2]. This family also includes integral membrane proteins currently uncharacterised. [1]. 24038693. Overexpression of fetA (ybbL) and fetB (ybbM), Encoding an Iron Exporter, Enhances Resistance to Oxidative Stress in Escherichia coli. Nicolaou SA, Fast AG, Nakamaru-Ogiso E, Papoutsakis ET;. Appl Environ Microbiol. 2013;79:7210-7219. [2]. 15659095. ALS3 encodes a phloem-localized ABC transporter-like protein that is required for aluminum tolerance in Arabidopsis. Larsen PB, Geisler MJ, Jones CA, Williams KM, Cancel JD;. Plant J. 2005;41:353-363. (from Pfam)

Date:

2024-10-16

ABC transporter permease is the transmembrane subunit found in a periplasmic binding protein (PBP)-dependent ABC transport system, which may be involved in the transport of one or more from a variety of substrates including sugars, ions, amino acids, and peptides, among others

Date:

2024-04-24