Protein Family Models

Dodecin is a flavin-binding protein [1],found in several bacteria and few archaea and represents a stand-alone version of the SHS2 domain [2]. It most closely resembles the SHS2 domains of FtsA and Rpb7p, and represents a single domain small-molecule binding form[1]. [1]. 15281131. The SHS2 module is a common structural theme in functionally diverse protein groups, like Rpb7p, FtsA, GyrI, and MTH1598/TM1083 superfamilies. Anantharaman V, Aravind L;. Proteins. 2004;56:795-807. [2]. 12679016. Crystal structure of halophilic dodecin: a novel, dodecameric flavin binding protein from Halobacterium salinarum. Bieger B, Essen LO, Oesterhelt D;. Structure. 2003;11:375-385. (from Pfam)

Date:

2024-10-16

dodecin family protein is a small flavin-binding protein that may function as a storage protein that sequesters various flavins and other cofactors, thereby protecting the cell against undesirable reactions mediated by the free cofactors

Date:

2021-01-28