Protein Family Models for Protein (Select 737615217) - Protein Family Models

Select item 4263481.

This domain is related to other HNH domain families such as Pfam:PF01844. Suggesting that these proteins have a nucleic acid cleaving function. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF025637.5
Method:: HMM

Select item 4131622.

HNH endonuclease

His-Asn-His (HNH) proteins are a very common family of small nucleic acid-binding proteins that are generally associated with endonuclease activity [4]. Named family as HNH. [1]. 7817395. Amino acid sequence motif of group I intron endonucleases is. conserved in open reading frames of group II introns.. Shub DA, Goodrich-Blair H, Eddy SR;. Trends Biochem Sci 1994;19:402-404.. Extended HNH family. [2]. 9358175. Statistical modeling and analysis of the LAGLIDADG family of. site-specific endonucleases and identification of an intein that. encodes a site-specific endonuclease of the HNH family.. Dalgaard JZ, Klar AJ, Moser MJ, Holley WR, Chatterjee A, Mian. IS;. Nucleic Acids Res 1997;25:4626-4638.. Named family as EX1HH-HX3H. [3]. 7920259. Self-splicing group I and group II introns encode homologous. (putative) DNA endonucleases of a new family.. Gorbalenya AE;. Protein Sci 1994;3:1117-1120.. [4]. 27131500. Biochemical characterization of a thermostable HNH endonuclease. from deep-sea thermophilic bacteriophage GVE2.. Zhang L, Huang Y, Xu D, Yang L, Qian K, Chang G, Gong Y, Zhou X,. Ma K;. Appl Microbiol Biotechnol. 2016;100:8003-8012. (from Pfam)

GO Terms:

Molecular Function:: nucleic acid binding (GO:0003676)

Molecular Function:: endonuclease activity (GO:0004519)

Molecular Function:: zinc ion binding (GO:0008270)

Date:: 2024-08-14

Family Accession:: NF013964.5
Method:: HMM

Select item 4006623.