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Links from Protein

Items: 13

1.

NAD-binding protein

3-Hydroxyisobutyrate is a central metabolite in the valine catabolic pathway, and is reversibly oxidised to methylmalonate semi-aldehyde by a specific dehydrogenase belonging to the 3-hydroxyacid dehydrogenase family. The reaction is NADP-dependent and this region of the enzyme binds NAD. The NAD-binding domain of 6-phosphogluconate dehydrogenase adopts an alpha helical structure [1]. [1]. 16126223. Crystal structure of novel NADP-dependent 3-hydroxyisobutyrate dehydrogenase from Thermus thermophilus HB8. Lokanath NK, Ohshima N, Takio K, Shiromizu I, Kuroishi C, Okazaki N, Kuramitsu S, Yokoyama S, Miyano M, Kunishima N;. J Mol Biol. 2005;352:905-917. (from Pfam)

GO Terms:
Molecular Function:
NAD binding (GO:0051287)
Date:
2024-10-16
Family Accession:
NF026183.5
Method:
HMM
2.

NAD(P)-binding domain-containing protein

Date:
2024-08-14
Family Accession:
NF015747.5
Method:
HMM
3.

NAD(P)-binding domain-containing protein

The NAD binding domain of 6-phosphogluconate dehydrogenase adopts a Rossmann fold. (from Pfam)

GO Terms:
Molecular Function:
NADP binding (GO:0050661)
Date:
2024-08-14
Family Accession:
NF015411.5
Method:
HMM
4.

3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein

The term 3-hydroxyacyl-CoA dehydrogenase, corresponding to EC 1.1.1.35, covers a range of specificities, as the acyl group is not specified. Beta-hydroxyacyl dehydrogenase is a synonym. There may be mulitple members of the family in a single genome, e.g. FadB, FabJ, and PaaH from Escherichia coli K-12.

GO Terms:
Biological Process:
fatty acid metabolic process (GO:0006631)
Molecular Function:
NAD+ binding (GO:0070403)
Date:
2024-10-16
Family Accession:
NF014757.5
Method:
HMM
5.
new record, indexing in progress
Family Accession:
6.
new record, indexing in progress
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7.
new record, indexing in progress
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8.
new record, indexing in progress
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9.
new record, indexing in progress
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10.
new record, indexing in progress
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11.
new record, indexing in progress
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12.
new record, indexing in progress
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13.

NAD(P)-dependent oxidoreductase

NAD(P)-dependent oxidoreductase similar to 3-hydroxyisobutyrate dehydrogenase, L-threonate dehydrogenase, 2-(hydroxymethyl)glutarate dehydrogenase, and glyoxylate/succinic semialdehyde reductase

Date:
2024-04-25
Family Accession:
11449905
Method:
Sparcle
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