Family member Swiss:P37875 is Bacillus subtilis stage V sporulation protein R, which is involved in spore cortex formation [1]. Little is known about cortex biosynthesis, except that it depends on several sigma E controlled genes, including spoVR [2]. Another family member is an uncharacterised protein YcgB. YcgB has been suggested to be part of a conserved signalling pathway with YeaH and YeaG. This pathway may be involved in nitrogen metabolism (see Supplementary note 5 in [3].) [1]. 8144469. Cloning and characterization of spoVR, a gene from Bacillus subtilis involved in spore cortex formation. Beall B, Moran CP Jr;. J Bacteriol 1994;176:2003-2012. [2]. 8982457. Molecular genetics of sporulation in Bacillus subtilis. Stragier P, Losick R;. Annu Rev Genet 1996;30:297-341. [3]. 29769716. Mutant phenotypes for thousands of bacterial genes of unknown function. Price MN, Wetmore KM, Waters RJ, Callaghan M, Ray J, Liu H, Kuehl JV, Melnyk RA, Lamson JS, Suh Y, Carlson HK, Esquivel Z, Sadeeshkumar H, Chakraborty R, Zane GM, Rubin BE, Wall JD, Visel A, Bristow J, Blow MJ, Arkin AP, Deutschbauer AM;. Nature. 2018;557:503-509. (from Pfam)
- Date:
- 2024-10-16