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Stage V sporulation protein AD (SpoVAD)
This family contains the bacterial stage V sporulation protein AD (SpoVAD), which is approximately 340 residues long. This is one of six proteins encoded by the spoVA operon, which is transcribed exclusively in the forespore at about the time of dipicolinic acid (DPA) synthesis in the mother cell. The functions of the proteins encoded by the spoVA operon are unknown, but it has been suggested they are involved in DPA transport during sporulation [1]. [1]. 11751839. The products of the spoVA operon are involved in dipicolinic acid uptake into developing spores of Bacillus subtilis. Tovar-Rojo F, Chander M, Setlow B, Setlow P;. J Bacteriol 2002;184:584-587. (from Pfam)
stage V sporulation protein AD
stage V sporulation protein AD (SpoVAD) may be involved in dipicolinic acid (DPA) transport during sporulation; similar to Bacillus subtilis SpoVAD
Bacillus and Clostridium species contain about 10 % dipicolinic acid (pyridine-2,6-dicarboxylic acid) by weight. This protein family, SpoVAD, belongs to the spoVA operon that is suggested to act in the transport of dipicolinic acid (DPA) from the mother cell, where DPA is synthesized, to the forespore, a process essential to sporulation. Members of this protein family are found, so far, in exactly those species believed capable of endospore formation.
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