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bifunctional DNA primase/polymerase
Members of this family adopt a structure consisting of a core of antiparallel beta sheets. They are found in various bacterial hypothetical proteins, and have been shown to harbour both primase and polymerase activities [1]. [1]. 14730355. Structure of a bifunctional DNA primase-polymerase. Lipps G, Weinzierl AO, von Scheven G, Buchen C, Cramer P;. Nat Struct Mol Biol. 2004;11:157-162. (from Pfam)
DNA primase/polymerase is a bifunctional protein that exhibits both primase and polymerase activities that preferentially use deoxynucleoside triphosphates (dNTPs) as substrates
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