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Motility related/secretion protein
This domain is found repeated three times in the N-terminal half of the gliding motility-related SprA proteins. The role of this domain in motility is uncertain [1]. It is also found in proteins required for secretion [2]. [1]. 17644580. Flavobacterium johnsoniae SprA is a cell surface protein involved in gliding motility. Nelson SS, Glocka PP, Agarwal S, Grimm DP, McBride MJ;. J Bacteriol. 2007;189:7145-7150. [2]. 17579257. Identification of a Porphyromonas gingivalis novel protein sov required for the secretion of gingipains. Saiki K, Konishi K;. Microbiol Immunol. 2007;51:483-491. (from Pfam)
cell surface protein SprA
cell surface protein SprA forms the protein-conducting channel of the T9SS translocon, a water-filled conduit across the outer membrane that is large enough to allow the passage of folded proteins
SprA is a cell surface protein widely distributed in the Bacteroidetes lineage. In Flavobacterium johnsoniae, a species that shows gliding motility, mutation disrupts gliding.
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