Protein Family Models

A family of uncharacterised proteins found by clustering human gut metagenomic sequences [1]. [1]. 20532204. Expansion of the protein repertoire in newly explored environments: human gut microbiome specific protein families. Ellrott K, Jaroszewski L, Weizhong L, Wooley J, Godzik, A. PLoS Computational Biology, 2010 (from Pfam)

Date:

2024-10-16

Members of this family adopt a structure consisting of a core of antiparallel beta sheets. They are found in various bacterial hypothetical proteins, and have been shown to harbour both primase and polymerase activities [1]. [1]. 14730355. Structure of a bifunctional DNA primase-polymerase. Lipps G, Weinzierl AO, von Scheven G, Buchen C, Cramer P;. Nat Struct Mol Biol. 2004;11:157-162. (from Pfam)

Date:

2024-10-16

This alpha helical domain is found at the C terminal of primases. [1]. 16027112. Origin and evolution of the archaeo-eukaryotic primase superfamily and related palm-domain proteins: structural insights and new members. Iyer LM, Koonin EV, Leipe DD, Aravind L;. Nucleic Acids Res. 2005;33:3875-3896. (from Pfam)

Date:

2024-10-16

protein containing domains Prim_Pol, PriCT_2, and DUF3987

Date:

2017-03-02