Protein Family Models for Protein (Select 873902850) - Protein Family Models

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Items: 4

Select item 4127431.

MGMT family protein

This is the C-terminal DNA-binding domain of 6-O-methylguanine-DNA methyltransferases [1]. [1]. 8156986. Crystal structure of a suicidal DNA repair protein: the Ada O6-methylguanine-DNA methyltransferase from E. coli. Moore MH, Gulbis JM, Dodson EJ, Demple B, Moody PC;. EMBO J 1994;13:1495-1501. (from Pfam)

GO Terms:

Molecular Function:: catalytic activity (GO:0003824)

Biological Process:: DNA repair (GO:0006281)

Date:: 2024-10-16

Family Accession:: NF013222.5
Method:: HMM

Select item 3900472.

new record, indexing in progress

Family Accession:

Select item 3475993.

new record, indexing in progress

Family Accession:

Select item 1953264.

MGMT family protein

MGMT (O-6-methylguanine DNA methyltransferase) family protein similar to MGMT, also called methylated-DNA--[protein]-cysteine S-methyltransferase, that repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme, resulting in its irreversible inactivation