Protein Family Models

Date:

2024-08-14

This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA. [1]. 9192620. Crystal structure of the homo-tetrameric DNA binding domain of. Escherichia coli single-stranded DNA-binding protein determined. by multiwavelength x-ray diffraction on the selenomethionyl. protein at 2.9-A resolution.. Raghunathan S, Ricard CS, Lohman TM, Waksman G;. Proc Natl Acad Sci U S A 1997;94:6652-6657.. [2]. 9033597. Crystal structure of human mitochondrial single-stranded DNA. binding protein at 2.4 A resolution.. Yang C, Curth U, Urbanke C, Kang C;. Nat Struct Biol 1997;4:153-157.. [3]. 9271227. A common core for binding single-stranded DNA: structural. comparison of the single-stranded DNA-binding proteins (SSB). from E. coli and human mitochondria.. Webster G, Genschel J, Curth U, Urbanke C, Kang C, Hilgenfeld R;. FEBS Lett 1997;411:313-316. (from Pfam)

Date:

2024-08-14

PriB binds single-stranded DNA at the primosome assembly site. This HMM describes a gamma-Proteobacterial form, usually encoded between rpsF (ribosomal protein S6) and rpsR (ribosomal protein S18).

Gene:

priB

Date:

2024-05-30

primosomal replication protein N (PriB) is one of three proteins involved in the PriA-dependent replication restart system which participate in the reconstruction of the replisome by further stabilizing the PriA-DNA complex and stimulating PriA helicase activity.

Date:

2022-08-08