Protein Family Models for Protein (Select 880808955) - Protein Family Models

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Items: 6

Select item 4286241.

This entry represents the second domain from the Csd3 peptidase [2]. This domain has a similar structure to Pfam:PF18059 despite low sequence similarity [2]. Paper describing PDB structure 2gu1. [1]. 18498110. Crystal structure of a putative lysostaphin peptidase from Vibrio cholerae. Ragumani S, Kumaran D, Burley SK, Swaminathan S;. Proteins. 2008;72:1096-1103. Paper describing PDB structure 4rny. [2]. 25760614. Structure of Csd3 from Helicobacter pylori, a cell shape-determining metallopeptidase. An DR, Kim HS, Kim J, Im HN, Yoon HJ, Yoon JY, Jang JY, Hesek D, Lee M, Mobashery S, Kim SJ, Lee BI, Suh SW;. Acta Crystallogr D Biol Crystallogr. 2015;71:675-686. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF039309.4
Method:: HMM

Select item 4115842.

peptidoglycan DD-metalloendopeptidase family protein

Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins such as Swiss:P33648 for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown. (from Pfam)