Protein Family Models

This domain is found at the N-terminus of a number of anti-sigma-factor antagonist proteins including B. subtilis RsbRD, Swiss:P54504. These proteins are negative regulators of the general stress transcription factor sigma(B) [1]. It is found in association with Pfam:PF01740. [1]. 15312768. A multicomponent protein complex mediates environmental stress signaling in Bacillus subtilis. Kim TJ, Gaidenko TA, Price CW;. J Mol Biol. 2004;341:135-150. (from Pfam)

Date:

2024-10-16

The STAS (after Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C terminal region of Sulphate transporters and bacterial antisigma factor antagonists. It has been suggested that this domain may have a general NTP binding function [2]. [1]. 9560229. Solution structure of SpoIIAA, a phosphorylatable component of the system that regulates transcription factor sigmaF of Bacillus subtilis. Kovacs H, Comfort D, Lord M, Campbell ID, Yudkin MD;. Proc Natl Acad Sci U S A 1998;95:5067-5071. [2]. 10662676. The STAS domain - a link between anion transporters and antisigma-factor antagonists. Aravind L, Koonin EV;. CurrBiol 2000;10:53-55. (from Pfam)

Date:

2024-10-16

STAS (Sulphate Transporter and Anti-Sigma factor antagonist) domain-containing protein similar to Bacillus subtilis RsbT co-antagonist protein RsbRD, which is one of four functionally non-identical RsbR paralogs that functions in the environmental signaling branch of the general stress response

Date:

2019-07-29