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SIR2 family protein
This family of proteins are related to the sirtuins. (from Pfam)
SIR2 family NAD-dependent protein deacylase
SIR2 family NAD-dependent protein deacylase such as NAD-dependent deacetylase, which catalyzes NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+, producing nicotinamide and the novel metabolite O-acetyl-ADP-ribose
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