Protein Family Models

This family is distantly related to Pfam:PF00062. Members are found in phages, type II, type III and type IV secretion systems (reviewed in [4]). [1]. 8203016. A conserved domain in putative bacterial and bacteriophage. transglycosylases.. Koonin EV, Rudd KE;. Trends Biochem Sci 1994;19:106-107.. [2]. 8692991. A family of lysozyme-like virulence factors in bacterial. pathogens of plants and animals.. Mushegian AR, Fullner KJ, Koonin EV, Nester EW;. Proc Natl Acad Sci U S A 1996;93:7321-7326.. [3]. 7548026. Structure of the 70-kDa soluble lytic transglycosylase complexed. with bulgecin A. Implications for the enzymatic mechanism.. Thunnissen AM, Rozeboom HJ, Kalk KH, Dijkstra BW;. Biochemistry 1995;34:12729-12737.. [4]. 14625683. Lytic transglycosylases in macromolecular transport systems of. Gram-negative bacteria.. Koraimann G;. Cell Mol Life Sci 2003;60:2371-2388. (from Pfam)

Date:

2024-08-14

The LysM (lysin motif) domain is about 40 residues long. It is found in a variety of enzymes involved in bacterial cell wall degradation [1]. This domain may have a general peptidoglycan binding function. The structure of this domain is known [2]. [1]. 1352512. Modular design of the Enterococcus hirae muramidase-2 and. Streptococcus faecalis autolysin.. Joris B, Englebert S, Chu CP, Kariyama R, Daneo-Moore L,. Shockman GD, Ghuysen JM;. FEMS Microbiol Lett 1992;70:257-264.. [2]. 10843862. The structure of a LysM domain from E. coli membrane-bound lytic. murein transglycosylase D (MltD).. Bateman A, Bycroft M;. J Mol Biol 2000;299:1113-1119. (from Pfam)

Date:

2024-08-14