Protein Family Models for Protein (Select 983472134) - Protein Family Models

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Items: 5

Select item 4121261.

phosphoribosyl-AMP cyclohydrolase

This enzyme catalyses the third step in the histidine biosynthetic pathway. It requires Zn ions for activity. [1]. 9931020. N1-(5'-phosphoribosyl)adenosine-5'-monophosphate cyclohydrolase: purification and characterization of a unique metalloenzyme. D'Ordine RL, Klem TJ, Davisson VJ;. Biochemistry 1999;38:1537-1546. (from Pfam)

GO Terms:

Biological Process:: L-histidine biosynthetic process (GO:0000105)

Molecular Function:: phosphoribosyl-AMP cyclohydrolase activity (GO:0004635)

Date:: 2024-10-16

Family Accession:: NF013653.5
Method:: HMM

Select item 3890132.

new record, indexing in progress

Family Accession:

Select item 3472323.

new record, indexing in progress

Family Accession:

Select item 215594.

HisI1 family protein

Date:: 2017-03-02

Family Accession:: 10000630
Method:: Sparcle

Select item 161695.

phosphoribosyl-AMP cyclohydrolase

Functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers