Protein Family Models

This family represents the periplasmic core domain found in a variety of ABC transporters. The structure of this family has been solved for the MacB protein [1]. Some structural similarity was found to the periplasmic domain of the AcrB multidrug efflux transporter. [1]. 19432486. Crystal structure of the periplasmic region of MacB, a noncanonic ABC transporter. Xu Y, Sim SH, Nam KH, Jin XL, Kim HM, Hwang KY, Lee K, Ha NC;. Biochemistry. 2009;48:5218-5225. (from Pfam)

Date:

2024-10-16

This is a family of predicted permeases and hypothetical transmembrane proteins. Swiss:P57382 has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both Swiss:P57382 and Swiss:O54500 have been shown to require ATP. This region contains three transmembrane helices. (from Pfam)

Date:

2024-08-14

lipoprotein-releasing ABC transporter permease subunit LolC is part of an ATP-dependent transport system LolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane

Date:

2019-07-29

This HMM describes the LolC protein, and its paralog LolE found in some species. These proteins are homologous to permease proteins of ABC transporters. In some species, two paralogs occur, designated LolC and LolE. In others, a single form is found and tends to be designated LolC.

Date:

2022-10-11

Gene:

lolC

Date:

2022-10-11