Abstract
Separase is the protease that cleaves the cohesive link between sister chromatids to trigger chromosome segregation in mitosis and meiosis. This enzyme is known to orchestrate additional mitotic events and we now gain new insight into how it promotes cytokinesis in the nematode Caenorhabditis elegans.
MeSH terms
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Animals
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Caenorhabditis elegans / cytology
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Caenorhabditis elegans / enzymology
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Caenorhabditis elegans Proteins / physiology
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Cell Cycle / physiology*
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Cell Cycle Proteins / physiology*
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Chromosome Segregation / physiology
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Cytokinesis / physiology
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Endopeptidases / physiology*
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Models, Biological
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Separase
Substances
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Caenorhabditis elegans Proteins
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Cell Cycle Proteins
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Endopeptidases
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SEP-1 protein, C elegans
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Separase