Abstract
CDP-diacylglycerol synthase, phosphatidylinositol synthase, and phosphatidylinositol kinase activities were associated with post-Golgi apparatus secretory vesicles destined for the plasma membrane of Saccharomyces cerevisiae. These results suggest that the plasma membrane is capable of synthesizing both CDP-diacylglycerol and phosphatidylinositol as well as phosphorylating phosphatidylinositol.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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1-Phosphatidylinositol 4-Kinase
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CDP-Diacylglycerol-Inositol 3-Phosphatidyltransferase
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Cell Membrane / enzymology
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Cytoplasmic Granules / enzymology*
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Macromolecular Substances
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Microsomes / enzymology
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Molecular Weight
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Nucleotidyltransferases / isolation & purification
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Nucleotidyltransferases / metabolism*
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Phosphatidylinositols / biosynthesis*
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Phosphotransferases / metabolism*
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Saccharomyces cerevisiae / enzymology*
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Saccharomyces cerevisiae Proteins*
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Transferases (Other Substituted Phosphate Groups)*
Substances
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Macromolecular Substances
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Phosphatidylinositols
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Saccharomyces cerevisiae Proteins
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Phosphotransferases
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1-Phosphatidylinositol 4-Kinase
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PIK1 protein, S cerevisiae
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Nucleotidyltransferases
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phosphatidate cytidylyltransferase
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Transferases (Other Substituted Phosphate Groups)
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CDP-Diacylglycerol-Inositol 3-Phosphatidyltransferase