Involvement of the phosphate regulon and the psiD locus in carbon-phosphorus lyase activity of Escherichia coli K-12

J Bacteriol. 1987 Apr;169(4):1753-6. doi: 10.1128/jb.169.4.1753-1756.1987.

Abstract

Escherichia coli K-12 can readily mutate to use methylphosphonic acid as the sole phosphorus source by a direct carbon-to-phosphorus (C-P) bond cleavage activity that releases methane and Pi. The in vivo C-P lyase activity is both physiologically and genetically regulated as a member of the phosphate regulon. Since psiD::lacZ(Mu d1) mutants cannot metabolize methylphosphonic acid, psiD may be the structural gene(s) for C-P lyase.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Escherichia coli / enzymology
  • Escherichia coli / genetics*
  • Genes
  • Genes, Bacterial*
  • Genes, Regulator
  • Lyases / genetics
  • Lyases / metabolism*
  • Mutation
  • Organophosphorus Compounds / metabolism
  • Phosphates / metabolism*

Substances

  • Organophosphorus Compounds
  • Phosphates
  • methylphosphonic acid
  • Lyases
  • carbon-phosphorus lyase