Platelet derived growth factor effect in the presence of Src family kinase inhibitors (MG-U74A)
Summary:
Analysis of NIH3T3 fibroblasts treated with platelet-derived growth factor (PDGF) and one of several Src family kinase (SFK) small molecule inhibitors. Inhibitors of SFKs, MEK1/2, and phosphotidylinositol 3-kinase used. Results provide insight into the role of SFKs in PDGF signaling.
GPL81:
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Citation:
Bromann PA, Korkaya H, Webb CP, Miller J et al. Platelet-derived growth factor stimulates Src-dependent mRNA stabilization of specific early genes in fibroblasts. J Biol Chem 2005 Mar 18;280(11):10253-63. PMID: 15637050
