DataSet Record GDS1112: Expression Profiles Data Analysis Tools Sample Subsets
Title: Glaucomatous astrocytes from the optic nerve head
Cluster AnalysisGDS1112 Cluster Image
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Summary: Expression profiling of astrocytes taken from the optic nerve head (ONH) of patients with glaucoma. The ONH is the site of damage in glaucomatous optic neuropathy. Studies suggest that damage in glaucoma is mediated by reactive astrocytes.
Organism: Homo sapiens
Platform: GPL8300: [HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array
Citations:
  • Hernandez MR, Agapova OA, Yang P, Salvador-Silva M et al. Differential gene expression in astrocytes from human normal and glaucomatous optic nerve head analyzed by cDNA microarray. Glia 2002 Apr 1;38(1):45-64. PMID: 11921203
  • Kompass KS, Agapova OA, Li W, Kaufman PL et al. Bioinformatic and statistical analysis of the optic nerve head in a primate model of ocular hypertension. BMC Neurosci 2008 Sep 26;9:93. PMID: 18822132
  • Nikolskaya T, Nikolsky Y, Serebryiskaya T, Zvereva S et al. Network analysis of human glaucomatous optic nerve head astrocytes. BMC Med Genomics 2009 May 9;2:24. PMID: 19426536
Reference Series: GSE2378 Sample count: 13
Value type: count Series published: 2005/03/09