DataSet Record GDS1236: Expression Profiles Data Analysis Tools Sample Subsets
Title: Huntingtin exon 1 protein overexpression
Cluster AnalysisGDS1236 Cluster Image
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Summary: Analysis of Htt14A2.5 cell line expressing a truncated form of huntingtin (Htt) exon 1 protein controlled by a promoter inducible by ponasterone (PA). Expression examined 48 hours after treatment with 5 uM PA. Htt expression in Htt14A2.5 results in protein aggregation.
Organism: Rattus norvegicus
Platform: GPL85: [RG_U34A] Affymetrix Rat Genome U34 Array
Citation:
  • Apostol BL, Illes K, Pallos J, Bodai L et al. Mutant huntingtin alters MAPK signaling pathways in PC12 and striatal cells: ERK1/2 protects against mutant huntingtin-associated toxicity. Hum Mol Genet 2006 Jan 15;15(2):273-85. PMID: 16330479
Reference Series: GSE2602 Sample count: 8
Value type: count Series published: 2005/05/30