CD4+ lymphocyte polarization into Th1 and Th2 cells in the presence of TGFbeta: time course (HG-U95A)
Summary:
Analysis of CD4+ lymphocyte induced to differentiate into Th1 and Th2 by treatment with IL-12 and IL-4 respectively in the presence of TGFbeta. Cells examined at various time points up to 48 hours after treatment. Results provide insight into the mechanisms regulating CD4+ cell polarization.
GPL8300:
[HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array
Citation:
Lund R, Aittokallio T, Nevalainen O, Lahesmaa R. Identification of novel genes regulated by IL-12, IL-4, or TGF-beta during the early polarization of CD4+ lymphocytes. J Immunol 2003 Nov 15;171(10):5328-36. PMID: 14607935
