Comparison of adrenal gland from spontaneously hypertensive (SHR) males at 4 weeks of age, a prehypertensive stage, and normotensive Wistar-Kyoto. Results compared to gene expression in hypertensive BPH mouse model, and provides insight into mechanisms of hypertension shared across species.
Friese RS, Mahboubi P, Mahapatra NR, Mahata SK et al. Common genetic mechanisms of blood pressure elevation in two independent rodent models of human essential hypertension. Am J Hypertens 2005 May;18(5 Pt 1):633-52. PMID: 15882546
Friese RS, Schmid-Schönbein GW, O'Connor DT. Systematic polymorphism discovery after genome-wide identification of potential susceptibility loci in a hereditary rodent model of human hypertension. Blood Press 2011 Aug;20(4):222-31. PMID: 21428728
