Rho/CRIK signaling modulation effect on keratinocyte
Summary:
Analysis of keratinocytes expressing activated Rho or Citron kinase (CRIK), or treated with C3 transferase. Rho plays a positive role during early differentiation, CRIK is a Rho effector, and C3 is a Rho inhibitor. Results provide insight into the role of Rho/CRIK in later stages of differentiation.
GPL81:
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Citation:
Grossi M, Hiou-Feige A, Tommasi Di Vignano A, Calautti E et al. Negative control of keratinocyte differentiation by Rho/CRIK signaling coupled with up-regulation of KyoT1/2 (FHL1) expression. Proc Natl Acad Sci U S A 2005 Aug 9;102(32):11313-8. PMID: 16061799
