Embryonal carcinoma cell line response to retinoic acid or trichostatin A
Summary:
Analysis of embryonal carcinoma cell line F9 following treatment with all-trans retinoic acid or trichostatin A, a histone deacetylase inhibitor (HDACI). Retinoic acid and HDACIs may be critical regulators of tissue homeostatis and are being tested in clinical trials for a variety of cancers.
GPL81:
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Citations:
Sangster-Guity N, Yu LM, McCormick P. Molecular profiling of embryonal carcinoma cells following retinoic acid or histone deacetylase inhibitor treatment. Cancer Biol Ther 2004 Nov;3(11):1109-20. PMID: 15467438
Chittur SV, Sangster-Guity N, McCormick PJ. Histone deacetylase inhibitors: a new mode for inhibition of cholesterol metabolism. BMC Genomics 2008 Oct 29;9:507. PMID: 18959802
