Embryonic kidney: ureteric bud and metanephric mesenchyme (RG-U34C)
Summary:
Analysis of ureteric buds (UBs) and metanephric mesenchyme (MM) from E13.5 kidneys. UB-secreted factors induce conversion of adjacent MM cells into nephrons. Results identify as potential regulators a set of 20 secreted molecules specific to the UB and conserved between species.
Schmidt-Ott KM, Yang J, Chen X, Wang H et al. Novel regulators of kidney development from the tips of the ureteric bud. J Am Soc Nephrol 2005 Jul;16(7):1993-2002. PMID: 15917337
