DataSet Record GDS2124: Expression Profiles Data Analysis Tools Sample Subsets
Title: ERK MAP kinase inactivation during G0/G1 to S phase transition: time course
Cluster AnalysisGDS2124 Cluster Image
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Summary: Analysis of NIH3T3 cells treated with the ERK inhibitor U0126 before or after the addition of the ERK activator FGF. Cells stimulated with FGF for up to 12 hours. Results identify genes regulated by the ERK pathway during G0/G1 to S phase transition.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citations:
  • Yamamoto T, Ebisuya M, Ashida F, Okamoto K et al. Continuous ERK activation downregulates antiproliferative genes throughout G1 phase to allow cell-cycle progression. Curr Biol 2006 Jun 20;16(12):1171-82. PMID: 16782007
  • Ebisuya M, Yamamoto T, Nakajima M, Nishida E. Ripples from neighbouring transcription. Nat Cell Biol 2008 Sep;10(9):1106-13. PMID: 19160492
Reference Series: GSE4739 Sample count: 19
Value type: count Series published: 2006/06/15