Analysis of short-term cultured glioblastoma cells treated with 5-aza-dC to induce DNA demethylation. Glioblastoma cells derived from 3 independent primary glioblastomas. Results provide insight into the role of epigenetic alterations in glioblastoma gene inactivation.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Mueller W, Nutt CL, Ehrich M, Riemenschneider MJ et al. Downregulation of RUNX3 and TES by hypermethylation in glioblastoma. Oncogene 2007 Jan 25;26(4):583-93. PMID: 16909125