Insulin-like growth factor-I decrease effect on the liver
Summary:
Analysis of livers of animals with decreased serum insulin-like growth factor-I (IGF-I) levels. The liver is the major source of serum IGF-I. The level of serum IGF-I is correlated to bone mineral density (BMD) and fracture risk. Results provide insight into the relationship between IGF-I and BMD.
Ackert-Bicknell CL, Salisbury JL, Horowitz M, DeMambro VE et al. A chromosomal inversion within a quantitative trait locus has a major effect on adipogenesis and osteoblastogenesis. Ann N Y Acad Sci 2007 Nov;1116:291-305. PMID: 17584978
