Large airway epithelium response to cigarette smoking (HG-133A)
Summary:
Analysis of large airway epithelial cells of phenotypically normal smokers. Lung cancer tumors exhibit neuroendocrine properties, and chronic smokers have increased numbers of neuroendocrine cells. Results provide insight into the effect of cigarette smoking on neuroendocrine cells.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Carolan BJ, Heguy A, Harvey BG, Leopold PL et al. Up-regulation of expression of the ubiquitin carboxyl-terminal hydrolase L1 gene in human airway epithelium of cigarette smokers. Cancer Res 2006 Nov 15;66(22):10729-40. PMID: 17108109