DataSet Record GDS2993: Expression Profiles Data Analysis Tools Sample Subsets
Title: Histone deacetylase 5 deficient nucleus accumbens response to cocaine
Cluster AnalysisGDS2993 Cluster Image
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Summary: Analysis of nuclei accumbens (NAc) from histone deacetylase 5 (HDAC5) mutants treated with cocaine for 7 days. The NAc is a major brain reward region; loss of HDAC5 causes hypersensitive responses to chronic cocaine. Results provide insight into the role of histone deacetylation in drug addiction.
Organism: Mus musculus
Platform: GPL4234: Sentrix Mouse-6 Expression BeadChip
Citation:
  • Renthal W, Maze I, Krishnan V, Covington HE 3rd et al. Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli. Neuron 2007 Nov 8;56(3):517-29. PMID: 17988634
Reference Series: GSE9134 Sample count: 30
Value type: transformed count Series published: 2007/09/27