DataSet Record GDS3001: Expression Profiles Data Analysis Tools Sample Subsets
Title: c-Jun N-terminal kinase 1 depletion effect on livers of diet-induced obese animals
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Summary: Analysis of c-Jun N-terminal kinase (JNK) 1 depleted livers of diet-induced obese (DIO) animals. The DIO animal is a model of mild obesity and insulin resistance. Results provide insight into the specific role of hepatic JNK1 in contributing to insulin resistance in DIO animals.
Organism: Mus musculus
Platform: GPL8321: [Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array
Citation:
  • Yang R, Wilcox DM, Haasch DL, Jung PM et al. Liver-specific knockdown of JNK1 up-regulates proliferator-activated receptor gamma coactivator 1 beta and increases plasma triglyceride despite reduced glucose and insulin levels in diet-induced obese mice. J Biol Chem 2007 Aug 3;282(31):22765-74. PMID: 17550900
Reference Series: GSE7648 Sample count: 14
Value type: count Series published: 2007/10/02