DataSet Record GDS3162: Expression Profiles Data Analysis Tools Sample Subsets
Title: Cochlea response to mitochondrial DNA mutations
Cluster AnalysisGDS3162 Cluster Image
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Summary: Analysis of cochleas of animals carrying a mutator allele of the mitochondrial (mt) Polg DNA polymerase. Accumulation of mtDNA mutations is associated with age-related hearing loss. Results provide insight into the role of mtDNA mutations in the pathogenesis of age-related hearing loss.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citation:
  • Someya S, Yamasoba T, Kujoth GC, Pugh TD et al. The role of mtDNA mutations in the pathogenesis of age-related hearing loss in mice carrying a mutator DNA polymerase gamma. Neurobiol Aging 2008 Jul;29(7):1080-92. PMID: 17363114
Reference Series: GSE4866 Sample count: 10
Value type: count Series published: 2007/05/18