Fetal brain response to maternal immune activation induced by lipopolysaccharide
Summary:
Analysis of fetal brains following maternal immune activation (MIA) induced by treating pregnant dams with lipopolysaccharide. MIA is a risk factor for the development of schizophrenia and autism. Results provide insight into the effect of MIA on the fetal brain at the molecular level.
GPL6247:
[RaGene-1_0-st] Affymetrix Rat Gene 1.0 ST Array [transcript (gene) version]
Citation:
Oskvig DB, Elkahloun AG, Johnson KR, Phillips TM et al. Maternal immune activation by LPS selectively alters specific gene expression profiles of interneuron migration and oxidative stress in the fetus without triggering a fetal immune response. Brain Behav Immun 2012 May;26(4):623-34. PMID: 22310921
