Analysis of whole blood from pediatric PFAPA patients during flares and asymptomatic intervals; hereditary autoinflammatory disease patients during flares were also examined. PFAPA is a common periodic fever disease in children. Results provide insight into the molecular basis of PFAPA pathogenesis.
GPL571:
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Citation:
Stojanov S, Lapidus S, Chitkara P, Feder H et al. Periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) is a disorder of innate immunity and Th1 activation responsive to IL-1 blockade. Proc Natl Acad Sci U S A 2011 Apr 26;108(17):7148-53. PMID: 21478439
