Primary keratinocyte response to in vitro cytokine exposure
Summary:
Analysis of cultured keratinocytes treated with various cytokines: interleukin-4, -13, -17A, interferon-α, -γ, or TNF. Marked proliferation of keratinocytes characterizes the chronic inflammatory skin disease psoriasis. Results provide insight into cytokine activity signatures in keratinocytes.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Swindell WR, Xing X, Stuart PE, Chen CS et al. Heterogeneity of inflammatory and cytokine networks in chronic plaque psoriasis. PLoS One 2012;7(3):e34594. PMID: 22479649
