Chronic high-level alcohol consumption effect on brain: post-mortem hippocampus
Summary:
Analysis of post-mortem hippocampus of chronic alcoholics (CAs). Chronic high-level alcohol consumption leads to decreased white matter and inhibition of neurogenesis. Results provide insight into molecular mechanisms that may play a role in the risk for alcoholism.
GPL6244:
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
McClintick JN, Xuei X, Tischfield JA, Goate A et al. Stress-response pathways are altered in the hippocampus of chronic alcoholics. Alcohol 2013 Nov;47(7):505-15. PMID: 23981442
