Non-Hodgkin’s lymphoma cell lines response to antibodies against CD20 or B-cell receptor
Summary:
Analysis of NHL lines treated with CD20 or B-cell receptor (BCR) antibodies. CD20 is a B cell-specific, cell surface protein; BCR has a key role in B cell development. Results provide insight into concordance in molecular changes following BCR activation and anti-CD20 Ab treatment in lymphoma cells.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Franke A, Niederfellner GJ, Klein C, Burtscher H. Antibodies against CD20 or B-cell receptor induce similar transcription patterns in human lymphoma cell lines. PLoS One 2011 Feb 18;6(2):e16596. PMID: 21364752
